Quantitative Breast Density in Contrast-Enhanced Mammography

Contrast-enhanced mammography (CEM) demonstrates a potential role in personalized screening models, particular for women at increased risk and with dense breasts. In this study, volumetric breast density (VBD) measured CEM images was compared VBD obtained from digital (DM) or tomosynthesis (DBT) images. A total of 150 who underwent between March 2019 December 2020, having least DM/DBT study performed before/after CEM, were included. Low-energy (LE-CEM) processed automatic software to obtain the VBD. VBDs paired datasets by Wilcoxon tests. multivariate regression model applied analyze relationship differences multiple independent variables certainly potentially affecting Median comparable LE-CEM (12.73% vs. 12.39%), not evidencing any statistically significant difference (p = 0.5855). DM associated glandular volume, thickness, compression force pressure, contact area, nipple-to-posterior-edge distance, i.e., reflecting positioning (coefficient determination 0.6023; correlation coefficient 0.7761). Volumetric low-energy contrast-enhanced spectral significantly different standard mammograms.